Tendon + Peritendinous Tissue Biology

Tendon and peritendinous tissue injury, remodeling, and healing across scales, integrating biomechanics and molecular pathways to understand function and recovery.

Key methods:

Glossary: Multi-omics · Interpretable ML

Key outputs

• Dataset/tool: Selected code + tools live on my GitHub (https://github.com/madavid128) and on the Projects page under Software & tools.

• Paper: Search the Publications page for tendon/repair work:

  tendon repair
• Figure: Representative images appear in Images.

What I work on

• Quantitative measures of tendon structure, cellularity, and mechanics
• Interactions between systemic factors (e.g., metabolic health) and repair
• Translational models that connect biology to functional outcomes

Key questions

• How do tendon and peritendinous tissues remodel after injury and repair?
• Which systemic factors (e.g., metabolic health) most strongly shape healing?
• What measurements best connect tissue biology to function?

Methods I use

• Histology and quantitative image analysis (including immunostaining where relevant)
• Preclinical models and functional/biomechanical readouts
• Reproducible analysis pipelines and statistics (with ML when useful)

Related publications

Images