Cartilage + Synovium Biology
Mechanisms of cartilage and synovium degeneration and repair in osteoarthritis and post-traumatic disease, linking tissue biology with translational outcomes.
Key methods:
Glossary: Spatial histopathology · Transcriptomics · Multi-omics · Interpretable ML
Key outputs
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Dataset/tool: Selected code + tools live on my GitHub (
https://github.com/madavid128) and on the Projects page under Software & tools. -
Paper: Search the Publications page for cartilage/synovium work:
- Figure: Representative images appear in Images.
What I work on
- Early tissue and cellular changes that precede gross degeneration
- Quantitative phenotyping across histology and imaging
- Translational models that connect biology to clinically relevant outcomes
Key questions
- What early cartilage and synovium changes predict later degeneration?
- How do cartilage and synovium interactions shape inflammation and repair?
- Which pathways are most actionable for translational intervention?
Methods I use
Related publications
Images
Scientific art | 2021
Scientific art | 2019
Scientific art | 2019
Scientific art | 2019
Scientific art | 2019
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Scientific art 2019